diff --git a/lib/adapters/fetch.js b/lib/adapters/fetch.js
index cf1c680..c569982 100644
--- a/lib/adapters/fetch.js
+++ b/lib/adapters/fetch.js
@@ -18,8 +18,9 @@ const fetchProgressDecorator = (total, fn) => {
 }
 
 const isFetchSupported = typeof fetch !== 'undefined';
+const isReadableStreamSupported = isFetchSupported && typeof ReadableStream !== 'undefined';
 
-const supportsRequestStreams = isFetchSupported && (() => {
+const supportsRequestStream = isReadableStreamSupported && (() => {
   let duplexAccessed = false;
 
   const hasContentType = new Request(platform.origin, {
@@ -36,15 +37,26 @@ const supportsRequestStreams = isFetchSupported && (() => {
 
 const DEFAULT_CHUNK_SIZE = 64 * 1024;
 
+const supportsResponseStream = isReadableStreamSupported && !!(()=> {
+  try {
+    return utils.isReadableStream(new Response('').body);
+  } catch(err) {
+    // return undefined
+  }
+})();
+
 const resolvers = {
-  stream: (res) => res.body
+  stream: supportsResponseStream && ((res) => res.body)
 };
 
-isFetchSupported && ['text', 'arrayBuffer', 'blob', 'formData'].forEach(type => [
-  resolvers[type] = utils.isFunction(Response.prototype[type]) ? (res) => res[type]() : (_, config) => {
-    throw new AxiosError(`Response type ${type} is not supported`, AxiosError.ERR_NOT_SUPPORT, config);
-  }
-])
+isFetchSupported && (((res) => {
+  ['text', 'arrayBuffer', 'blob', 'formData', 'stream'].forEach(type => {
+    !resolvers[type] && (resolvers[type] = utils.isFunction(res[type]) ? (res) => res[type]() :
+      (_, config) => {
+        throw new AxiosError(`Response type '${type}' is not supported`, AxiosError.ERR_NOT_SUPPORT, config);
+      })
+  });
+})(new Response));
 
 const getBodyLength = async (body) => {
   if(utils.isBlob(body)) {
@@ -74,7 +86,7 @@ const resolveBodyLength = async (headers, body) => {
   return length == null ? getBodyLength(body) : length;
 }
 
-export default async (config) => {
+export default isFetchSupported && (async (config) => {
   let {
     url,
     method,
@@ -106,7 +118,7 @@ export default async (config) => {
   }
 
   try {
-    if (onUploadProgress && supportsRequestStreams && method !== 'get' && method !== 'head') {
+    if (onUploadProgress && supportsRequestStream && method !== 'get' && method !== 'head') {
       let requestContentLength = await resolveBodyLength(headers, data);
 
       let _request = new Request(url, {
@@ -145,7 +157,7 @@ export default async (config) => {
 
     const isStreamResponse = responseType === 'stream' || responseType === 'response';
 
-    if (onDownloadProgress || isStreamResponse) {
+    if (supportsResponseStream && (onDownloadProgress || isStreamResponse)) {
       const options = {};
 
       Object.getOwnPropertyNames(response).forEach(prop => {
@@ -192,6 +204,6 @@ export default async (config) => {
 
     throw AxiosError.from(err, code, config, request);
   }
-}
+});
 
 
diff --git a/package.json b/package.json
index 46f751a..82c8ef4 100644
--- a/package.json
+++ b/package.json
@@ -216,4 +216,4 @@
       "@commitlint/config-conventional"
     ]
   }
-}
\ No newline at end of file
+}